Basic networks: definition and applications.
نویسندگان
چکیده
We define basic networks as the undirected subgraphs with minimal number of units in which the distances (geodesics, minimal path lengths) among a set of selected nodes, which we call seeds, in the original graph are conserved. The additional nodes required to draw the basic network are called connectors. We describe a heuristic strategy to find the basic networks of complex graphs. We also show how the characterization of these networks may help to obtain relevant biological information from highly complex protein-protein interaction data.
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عنوان ژورنال:
- Journal of theoretical biology
دوره 258 1 شماره
صفحات -
تاریخ انتشار 2009